Patient details
- Name
- Mr N.T.
- Age / sex
- 59-year-old man
- Occupation
- Taxi driver
- Marital status
- Married
- Seen
- Surgical clinic, 11:00
- Clerked
- Surgical clinic, 11:20
- Source
- Patient himself, reliable
- Referred by
- Pharmacist, then family doctor
Presenting complaint
“I have been passing fresh blood with my stool for three months.”
History of presenting complaint
Mr N.T. was well until three months ago, when he first noticed bright red blood when opening his bowels. The blood is mixed with the stool and also coats its surface, and there is often slimy mucus with it. The amount is small each time, without clots, but it now happens on most days and is increasing. Passing stool is not painful. Over the same three months his bowel habit has changed: he used to pass one formed stool each morning and now goes three or four times a day, with looser and narrower stools, an urgent need to go in the morning, and a feeling that the bowel has not emptied afterwards. He has lost 6 kg in three months without trying, and his appetite is reduced. For the last month he has felt tired and becomes breathless climbing stairs. He thought the bleeding was from piles and used a cream from the pharmacy for six weeks without benefit. He has no pain at the anus, no lump coming down and no itching. He has no abdominal pain, swelling or vomiting. He has passed no black stools and has not vomited blood. He has had no fever, no diarrhoea at night, no mouth ulcers or joint pains, and no similar episodes in earlier years. He has not travelled recently or taken antibiotics. He has no urinary symptoms, no bone pain and no jaundice. He has never had a colonoscopy.
Past medical history
No chronic illness. No previous bowel disease or polyps.
Past surgical history
No previous operations.
Drugs and allergies
No regular medication. No aspirin, anti-inflammatory drugs or anticoagulants. No iron tablets.
No known drug allergies.
Family history
His father had cancer of the colon at 64. No other relatives with bowel cancer or polyps.
Social history
Smokes 20 cigarettes a day for 25 years (25 pack-years). No alcohol. Eats red meat most days and few vegetables. Sits for most of the day.
Systems review
No cough or chest pain. No headache.
General examination
A thin man, comfortable at rest. Alert and orientated. Conjunctivae pale. Not jaundiced. Weight 76 kg.
Nails normal. No enlarged lymph node in the left supraclavicular fossa. No ankle swelling.
Abdominal examination
Abdomen not distended. No scars. Soft and not tender. No mass felt, including in the right iliac fossa. Liver not palpable, span 11 cm. Spleen not palpable. No shifting dullness. Bowel sounds normal. No enlarged inguinal lymph nodes.
Anorectal examination
Performed with consent and a chaperone, in the left lateral position with the knees drawn up.
Inspection
Perianal skin normal. No skin tags, no fissure, no external piles, no fistula opening, nothing coming down on straining.
Digital examination
Anal tone normal and the examination is not painful. A hard, irregular, ulcerated mass is felt on the posterior wall of the rectum. Its lower edge is about 6 cm from the anal verge and its upper limit cannot be reached. It occupies about half of the circumference and moves on the tissues beneath it. The prostate is felt separately in front and is normal. Blood and mucus on the glove.
Other systems
Chest: clear.
Heart: first and second heart sounds normal, soft flow murmur.
Legs: no swelling.
Summary
Provisional diagnosis
Carcinoma of the rectum, with probable iron deficiency anaemia.
Plan
- Bloods: full blood count, ferritin, urea and electrolytes, liver function tests, CEA as a baseline.
- Colonoscopy with biopsy of the mass and inspection of the whole colon.
- Staging: CT of the chest, abdomen and pelvis, and MRI of the pelvis.
- Discussion at the multidisciplinary meeting.
- Results and diagnosis to be explained by the consultant.
Differential diagnosis of fresh rectal bleeding
Group the causes by site: anus, rectum and colon. Use the pattern of the blood and the presence of pain to separate them.
| Diagnosis | Points to it in the history | Points to it on examination | In this patient |
|---|---|---|---|
| Anus | |||
| Haemorrhoids | Bright blood after the stool, dripping into the pan or on the paper; painless; lump that comes down | Often nothing outside; seen on proctoscopy | Blood is mixed in; there is a mass |
| Anal fissure | Sharp pain on passing stool lasting minutes to hours, streak of blood on the paper, constipation | Tear at the back of the anal margin with a skin tag; examination too painful | No pain |
| Anal cancer | Pain, bleeding, lump at the anus | Hard ulcer at the anal margin, groin nodes | Anus normal |
| Rectum | |||
| Carcinoma of the rectum | Blood and mucus mixed with stool, tenesmus, change in bowel habit, weight loss | Hard irregular mass on rectal examination | Most likely |
| Rectal polyp | Painless bleeding, sometimes mucus; no weight loss | Soft mobile lump on a stalk | Mass is hard and ulcerated |
| Proctitis | Urgency, blood and mucus, frequent small stools; ulcerative colitis or past radiotherapy | Tender, granular rectal wall | Discrete mass |
| Colon | |||
| Cancer of the left colon | Change in bowel habit, blood mixed with stool, colicky pain | Sometimes a mass in the left abdomen | Possible second tumour; colonoscopy |
| Cancer of the right colon | Tiredness and anaemia with little visible blood, weight loss | Mass in the right iliac fossa, pallor | No mass |
| Diverticular bleeding | Older patient, sudden large painless bleed that stops by itself | Normal examination | Small daily bleeds for months |
| Angiodysplasia | Elderly, repeated painless bleeds, anaemia | Normal examination | Does not explain the mass |
| Ulcerative colitis or Crohn's disease | Young adult, bloody diarrhoea for weeks, night stools, mouth ulcers, joint pains | Thin, tender abdomen | Wrong age, no such symptoms |
| Infective colitis | Sudden bloody diarrhoea with fever; travel, contacts | Fever, tender abdomen | Three months, no fever |
| Ischaemic colitis | Elderly with vascular disease, sudden pain then bloody diarrhoea | Left-sided tenderness | No pain |
| Upper gut | |||
| Fast bleeding from stomach or duodenum | Ulcer history, vomiting blood, black stools, collapse | Fast pulse, low blood pressure | Stable, no black stools |
Clinical signs related to this case
The signs you should look for in any patient with rectal bleeding. For each one, know how to elicit it and what a positive result means.
| Sign | How to elicit it, or what you see | What it means |
|---|---|---|
| General signs | ||
| Pallor | Pale conjunctivae and palm creases | Chronic blood loss |
| Spoon-shaped nails | Nails flat or curved upwards | Long-standing iron deficiency |
| Fast pulse with low blood pressure | Check lying and sitting if safe | Acute significant bleed: resuscitate first |
| Virchow's node | Hard node in the left supraclavicular fossa | Spread from an abdominal cancer |
| Signs in the abdomen | ||
| Mass in the right iliac fossa | Firm mass that does not move with breathing | Cancer of the caecum, or Crohn's disease |
| Hard irregular liver | Knobbly edge below the costal margin | Liver deposits |
| Shifting dullness | Flank dullness that moves when the patient turns | Fluid from spread of cancer |
| Distension with a drum-like note | Swollen resonant abdomen | The tumour is obstructing |
| Signs at the anus | ||
| Sentinel skin tag | Small tag at the back of the anal margin with a tear above it | Chronic anal fissure |
| Prolapsing haemorrhoids | Bluish cushions at 3, 7 and 11 o'clock that come down on straining | Haemorrhoids. Their presence does not explain a change in bowel habit. |
| Fistula opening or abscess | Small opening or tender swelling beside the anus | Perianal sepsis; consider Crohn's disease if multiple |
| Signs on rectal examination | ||
| Hard, irregular mass | Describe wall, distance, circumference, surface, upper limit, mobility | Rectal cancer |
| Soft mobile lump on a stalk | Slips away from the finger | Polyp |
| Blood and mucus on the glove | Look every time and record the colour | Bright red: lower bowel. Dark or black: higher up. |
| Hard nodules felt in front of the rectum | A firm shelf above the prostate or cervix | Deposits in the pelvis from a cancer in the abdomen |
| Enlarged inguinal nodes | Hard nodes in the groin | Anal cancer below the dentate line drains to the groin; rectal cancer does not |
Teaching case. The patient is fictional and written to illustrate format and reasoning. Local protocols decide investigation and treatment.