PSPal Surgery

Case 6 of 12Lumps48-year-old woman

Breast lump

A model clerking. Read the left column as the record you would write; read the boxes on the right for why it is written that way.

Patient details

Name
Mrs H.M.
Age / sex
48-year-old woman
Occupation
Schoolteacher
Marital status
Married, two children
Seen
Breast clinic, 09:30
Clerked
Breast clinic, 09:45
Source
Patient herself, reliable
Referred by
Family doctor

Presenting complaint

“A lump in my left breast for six weeks.”

History of presenting complaint

Mrs H.M. was well until six weeks ago, when she felt a lump in the upper outer part of her left breast while showering. It was then the size of a chickpea and is now the size of a walnut. It is painless and feels hard, and it does not change in size or tenderness with her periods. She has noticed no discharge from the nipple, no change in the shape or direction of the nipple, and no dimpling, redness or ulceration of the skin. She has not felt a lump in either armpit, and her right breast is normal. She has had no previous breast lumps, biopsies or breast operations, no injury to the breast, and no fever; she is not breastfeeding. She has no bone or back pain, no cough or breathlessness, no jaundice or abdominal swelling, no headache and no weight loss. Her periods began at the age of 11 and are still regular, the last one starting ten days ago. She had her first child at 31 and has two children, each breastfed for about three months. She took the oral contraceptive pill for eight years in the past and has never used hormone replacement. She has had no radiotherapy to the chest. Her mother was treated for breast cancer at 52 and a maternal aunt had ovarian cancer. She has never had a mammogram. She is frightened that this is the same disease her mother had.

Past medical history

No chronic illness.

Past surgical history

One caesarean section in 2012, with no complications.

Drugs and allergies

No regular medication. No known drug allergies.

Family history

Mother: breast cancer at 52, alive. Maternal aunt: ovarian cancer at 60. No male breast cancer in the family.

Social history

Does not smoke or drink alcohol. Lives with her husband and two children.

General examination

A well-looking woman, anxious but comfortable. Not pale, not jaundiced. Weight 68 kg, with no recent change.

Temperature36.7 °C
Pulse82 /min, regular
Blood pressure124/76 mmHg
Respiratory rate14 /min
Oxygen saturation99% on air

Breast examination

Examined with consent, in the presence of a female chaperone, undressed to the waist.

Inspection

Sitting with arms by her sides, then raised above the head, then with hands pressed on the hips. The breasts are of similar size. On raising the arms, dimpling of the skin appears over the upper outer quadrant of the left breast. Both nipples are at the same level and point outwards, with no discharge and no scaling. No redness, no orange-peel skin, no visible veins, no scars.

Palpation

Lying at 45 degrees with the hand behind the head. The right breast was examined first and is normal. In the left breast there is a single lump in the upper outer quadrant, at 2 o'clock, 5 cm from the nipple. It measures 3 by 2.5 cm, is hard, with an irregular surface and an ill-defined edge, and is not tender or warm. The skin over it dimples when the lump is moved, so it is tethered to the skin. It moves freely over the chest wall both with the pectoral muscle relaxed and with it tensed. No other lumps. No discharge when she presses the nipple herself.

Lymph nodes

Left axilla: two firm, mobile, non-tender nodes of about 1 cm in the central group. Right axilla: no nodes. No nodes in either supraclavicular fossa.

Other systems

Chest: clear, no pleural effusion.

Abdomen: liver not palpable, no ascites.

Spine: no tenderness on percussion.

Arms: no swelling.

Summary

Say this to the examinerMrs H.M. is a 48-year-old premenopausal woman whose mother had breast cancer, who presents with a painless, enlarging lump in the left breast for six weeks. On examination there is a 3 cm hard, irregular lump in the upper outer quadrant of the left breast, tethered to the skin and not fixed to the chest wall, with two mobile nodes in the left axilla and no clinical evidence of distant spread.

Provisional diagnosis

Carcinoma of the left breast, clinical stage T2 N1 M0.

Plan

  • Complete the triple assessment: clinical examination, imaging and tissue diagnosis.
  • Mammography of both breasts and ultrasound of the left breast and axilla.
  • Core needle biopsy of the lump, with hormone receptor and HER2 status. Sampling of an axillary node if abnormal on ultrasound.
  • Results to be given by the consultant, and the case discussed at the multidisciplinary meeting.
  • Referral for genetic counselling in view of the family history.

Differential diagnosis of a breast lump

Use the age of the patient and the character of the lump. Say which features are for and against in your patient.

DiagnosisPoints to it in the historyPoints to it on examinationIn this patient
Malignant
Carcinoma of the breastOver 35, painless growing lump, family history, no change with periodsHard, irregular, ill-defined, tethered to skin, axillary nodesMost likely
Phyllodes tumourRapidly growing large lump, age 40 to 50Large, smooth, mobile, lobulated; skin stretched and shinyLump is small and irregular
Benign lumps
FibroadenomaAge 15 to 30, slow growing, painlessFirm, smooth, well-defined, very mobileWrong age, wrong character
Breast cystAge 35 to 50, appears quickly, may be tenderSmooth, tense or fluctuant, well-definedHard and irregular
Fibrocystic changeLumpiness and pain in both breasts that vary with the cycleIll-defined nodular areas, often both upper outer quadrantsNo cyclical change
Fat necrosisInjury or surgery to the breast, sometimes forgottenHard, irregular, may tether the skin; imitates cancerNo injury; biopsy decides
Breast abscessBreastfeeding, pain, feverHot, red, tender, fluctuantNot lactating, not tender
Duct ectasia and periductal mastitisSmoker, around menopause, green or creamy dischargeLump beneath the areola, slit-like nipple retractionLump is far from the nipple
Intraductal papillomaBlood-stained discharge from a single ductSmall lump near the areola or noneNo discharge
GalactoceleRecently stopped breastfeedingSmooth, mobile, non-tender cystNot applicable
LipomaSlow growing for yearsSoft, lobulatedHard lump
Not from the breast
Sebaceous cystLump in the skin with a punctumMoves with the skinLump is in the breast
CostochondritisPain over the ribs, worse on movementTender rib junction, no breast lumpNo pain
Model OSCE answer“I have completed the clinical part of the triple assessment. My diagnosis is carcinoma of the left breast, because she is 48 with a family history, and the lump is hard, irregular, ill-defined and tethered to the skin, with mobile axillary nodes. Clinically this is T2 N1 M0. My differentials are fat necrosis, which can imitate cancer exactly, a breast cyst and fibrocystic change, but none explains the nodes. I would complete the triple assessment with mammography and ultrasound and a core biopsy.”

Clinical signs related to this case

The signs you should look for in any patient with a breast lump. For each one, know how to elicit it and what a positive result means.

SignHow to elicit it, or what you seeWhat it means
Signs in the skin
Skin dimplingAppears or deepens when the arms are raised or the lump is movedTethering: the tumour is pulling on the ligaments of the breast
Orange-peel skinThickened skin with pitting at the hair folliclesSkin lymphatics are blocked by tumour: locally advanced cancer
Redness and warmth of the whole breastSwollen, red, warm breast without fever, not breastfeedingInflammatory breast cancer, often mistaken for infection
Ulceration or skin nodulesTumour breaking through the skin, or small nodules around itLocally advanced cancer
Signs at the nipple
Recent nipple retractionNipple pulled in or changed direction over weeks or monthsCancer beneath the nipple. A slit-like retraction for years suggests duct ectasia.
Blood-stained discharge from one ductAsk the patient to express it herself; note the colour and whether one duct or severalIntraductal papilloma or cancer
Eczema of the nipple (Paget's disease)Red, scaly, crusted nipple on one side that destroys the nippleUnderlying breast cancer. Ordinary eczema affects the areola, both sides, and spares the nipple.
Signs of the lump
Fixation to the pectoral muscleMobility of the lump is lost when she presses her hands on her hipsTumour has invaded the muscle
Fixation to the chest wallLump cannot be moved even with the muscle relaxedTumour has invaded the chest wall: T4
Very mobile lumpFirm smooth lump that slips away from the fingersFibroadenoma, the “breast mouse”
FluctuationSmooth, tense lump that transmits pressure between two fingersCyst
Signs of spread
Axillary nodesHard nodes; mobile, or matted together and fixedMobile: N1. Fixed or matted: N2.
Supraclavicular nodeHard node above the clavicle on the same sideN3 disease
Swelling of the armWhole arm swollen on the affected sideAxillary lymphatics blocked by tumour, or previous axillary surgery
Tender spine, hard liver, pleural effusionPercuss the spine, palpate the liver, percuss the lung basesDistant spread

Teaching case. The patient is fictional and written to illustrate format and reasoning. Local protocols decide investigation and treatment.